Impedance Spectroscopy for in Situ Biomass Measurements in Microbioreactors

نویسندگان

  • S. Goh
  • R. J. Ram
چکیده

Mammalian cells dominate the biopharmaceutical industry and maintaining cell viability is a limiting factor in most mammalian cell cultures. This project is focused on developing an online (in-situ) dielectric spectroscopy sensor that is capable of measuring cell viability in real-time to enable optimization of culture conditions for Chinese Hamster Ovary (CHO) cell lines in micro-bioreactors.

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تاریخ انتشار 2010